快速導航
學歷類
職業資格
公務員
醫衛類
建筑工程
外語類
外貿類
計算機類
財會類
技能鑒定
new weapon to fight cancer
1. British scientists are preparing to launch trials of a radical new way to
fight cancer, which kills tumours by infecting them with viruses like the common
cold.
2. If successful, virus therapy could eventually form a third pillar
alongside radiotherapy and chemotherapy in the standard arsenal against cancer,
while avoiding some of the debilitating side-effects.
3. Leonard Seymour, a professor of gene therapy at Oxford University, who has
been working on the virus therapy with colleagues in London and the US, will
lead the trials later this year. Cancer Research UK said yesterday that it was
excited by the potential of Prof Seymour’s pioneering techniques.
4. One of the country’s leading geneticists, Prof Seymour has been working
with viruses that kill cancer cells directly, while avoiding harm to healthy
tissue. "In principle, you’ve got something which could be many times more
effective than regular chemotherapy," he said.
5. Cancer-killing viruses exploit the fact that cancer cells suppress the
body’s local immune system. "If a cancer doesn’t do that, the immune system
wipes it out. If you can get a virus into a tumour, viruses find them a very
good place to be because there’s no immune system to stop them replicating. You
can regard it as the cancer’s Achilles’ heel."
6. Only a small amount of the virus needs to get to the cancer. "They
replicate, you get a million copies in each cell and the cell bursts and they
infect the tumour cells adjacent and repeat the process," said Prof Seymour.
7. Preliminary research on mice shows that the viruses work well on tumours
resistant to standard cancer drugs. "It’s an interesting possibility that they
may have an advantage in killing drug-resistant tumours, which could be quite
different to anything we’ve had before."
8. Researchers have known for some time that viruses can kill tumour cells
and some aspects of the work have already been published in scientific journals.
American scientists have previously injected viruses directly into tumours but
this technique will not work if the cancer is inaccessible or has spread
throughout the body.
9. Prof Seymour’s innovative solution is to mask the virus from the body’s
immune system, effectively allowing the viruses to do what chemotherapy drugs do
- spread through the blood and reach tumours wherever they are. The big hurdle
has always been to find a way to deliver viruses to tumours via the bloodstream
without the body’s immune system destroying them on the way.
10. "What we’ve done is make chemical modifications to the virus to put a
polymer coat around it - it’s a stealth virus when you inject it," he said.
11. After the stealth virus infects the tumour, it replicates, but the copies
do not have the chemical modifications. If they escape from the tumour, the
copies will be quickly recognised and mopped up by the body’s immune system.
12. The therapy would be especially useful for secondary cancers, called
metastases, which sometimes spread around the body after the first tumour
appears. "There’s an awful statistic of patients in the west ... with malignant
cancers; 75% of them go on to die from metastases," said Prof Seymour.
13. Two viruses are likely to be examined in the first clinical trials:
adenovirus, which normally causes a cold-like illness, and vaccinia, which
causes cowpox and is also used in the vaccine against smallpox. For safety
reasons, both will be disabled to make them less pathogenic in the trial, but
Prof Seymour said he eventually hopes to use natural viruses.
14. The first trials will use uncoated adenovirus and vaccinia and will be
delivered locally to liver tumours, in order to establish whether the treatment
is safe in humans and what dose of virus will be needed. Several more years of
trials will be needed, eventually also on the polymer-coated viruses, before the
therapy can be considered for use in the NHS. Though the approach will be
examined at first for cancers that do not respond to conventional treatments,
Prof Seymour hopes that one day it might be applied to all cancers.
Questions 1-6
Do the following statements agree with the information given in the reading
passage? For questions 1-6 write
TRUE if the statement agrees with the information
FALSE if the statement contradicts the information
NOT GIVEN if there is no information on this in the passage
1.Virus therapy, if successful, has an advantage in eliminating
side-effects.
2.Cancer Research UK is quite hopeful about Professor Seymour’s work on the
virus therapy.
3.Virus can kill cancer cells and stop them from growing again.
4.Cancer’s Achilles’ heel refers to the fact that virus may stay safely in a
tumor and replicate.
5.To infect the cancer cells, a good deal of viruses should be injected into
the tumor.
6.Researches on animals indicate that virus could be used as a new way to
treat drug-resistant tumors.
Question 7-9
Based on the reading passage, choose the appropriate letter from A-D for each
answer.
7.Information about researches on viruses killing tumor cells can be
found
(A) on TV
(B) in magazines
(C) on internet
(D) in newspapers
8.To treat tumors spreading out in body, researchers try to
(A) change the body’ immune system
(B) inject chemotherapy drugs into bloodstream.
(C) increase the amount of injection
(D) disguise the viruses on the way to tumors.
9.When the chemical modified virus in tumor replicates, the copies
(A) will soon escape from the tumor and spread out.
(B) will be wiped out by the body’s immune system.
(C) will be immediately recognized by the researchers.
(D) will eventually stop the tumor from spreading out.
Questions 10-13
Complete the sentences below. Choose your answers from the list of words. You
can only use each word once.
NB There are more words in the list than spaces so you will not use them
all.
In the first clinical trials, scientists will try to ……10…… adenovirus and
vaccinia, so both the viruses will be less pathogenic than the ……11…….These
uncoated viruses will be applied directly to certain areas to confirm safety on
human beings and the right ……12…… needed. The experiments will firstly be
……13……to the treatment of certain cancers
主站蜘蛛池模板：
两个人的www免费视频|
无码福利在线观看1000集|
99久久精品无码一区二区三区|
国产精品成人aaaaa网站|
乱色欧美激惰|
亚洲国产精品成人网址天堂|
国产精品久久福利网站|
亚洲精品久久无码av片软件|
无码人妻啪啪一区二区|
久久精品午夜一区二区福利|
99久久免费只有精品国产|
精品无码久久久久久久动漫|
国产一在线精品一区在线观看|
无码成人片在线播放|
国产午夜无码精品免费看动漫|
精品乱人伦一区二区三区|
久女女热精品视频在线观看|
男女无遮挡xx00动态图120秒|
亚洲欧洲日韩国内高清|
国产精品一久久香蕉国产线看观看|
伊人伊成久久人综合网|
亚洲精品久久久久久中文|
插我舔内射18免费视频|
亚洲av综合一区二区在线观看|
韩国午夜理伦三级在线观看仙踪林|
性色香蕉av久久久天天网|
欧洲精品成人免费视频在线观看|
性刺激的欧美三级视频中文字幕|
久久久久无码精品国产|
精品人妻无码区在线视频|
亚洲爆乳精品无码一区二区|
亚洲精品久久久一区|
www插插插无码视频网站|
人妻人人澡人人添人人爽人人玩|
色香欲天天天影视综合网|
无码av一区二区三区无码|
国产精品美女乱子伦高|
人妻少妇精品久久|
亚洲欧美精品aaaaaa片|
亚洲a综合一区二区三区|
国产无套内射又大又猛又粗又爽|
